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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2200 | S6 Kinase Substrate Peptide 32 | Others | |
S6 Kinase Substrate Peptide 32 is a peptide that measures the activity of kinases that phosphorylate ribosomal protein S6. It can also be used as a substrate. | |||
T6S1302 | Carnosol | Nrf2 , Endogenous Metabolite , S6 Kinase | |
Carnosol is an Nrf2 activator, increasing Nrf2 levels and promoting heme oxygenase 1 (HMOX1) expression. It is a ribosomal S6 kinase (RSK2) inhibitor and can be used in gastric cancer-related research with an IC50 value ... | |||
T3836 | Eudesmin | MAPK , S6 Kinase | |
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m... | |||
T22422 | S6K-18 | S6 Kinase | |
S6K-18, a highly selective S6K1 inhibitor, inhibits S6K1 with IC50 of 52nM. | |||
T5428 | BIX 02565 | LRRK2 , S6 Kinase | |
BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM). | |||
T6304 | AT7867 | Akt , PKA , S6 Kinase | |
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family. | |||
T6877 | LJH685 | Apoptosis , S6 Kinase | |
LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM). | |||
T2482 | AT13148 | ROCK , SGK , Akt , PKA , S6 Kinase | |
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II. | |||
T2002 | PF-4708671 | PF4708671 | S6 Kinase , Autophagy |
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671(PF4708671) is potent for S6K1(Ki50=20 nM, IC50=160 nM). | |||
T4488 | GSK-25 | GSK25 | ROCK , S6 Kinase , mTOR |
GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested). | |||
T4301 | AD80 | Raf , c-RET , Src , S6 Kinase | |
AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity. | |||
T6171 | BI-D1870 | S6 Kinase , Autophagy | |
BI-D1870 is a cell-permeable, ATP-competitive inhibitor of ribosomal S6 kinases (RSKs; IC50s: 31/24/18/15 nM for RSK1/2/3/4). | |||
T6878 | LJI308 | S6 Kinase | |
LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. | |||
T14779 | BRD7389 | SGK , FLT , Pim , CDK , S6 Kinase , DAPK | |
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively. | |||
T6948 | Pluripotin | SC1 | ERK , Raf , S6 Kinase |
Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. | |||
T6159 | LY-2584702 free base | S6 Kinase , mTOR | |
LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM). | |||
T7790 | Bisindolylmaleimide V | PKC , S6 Kinase | |
Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor. | |||
T1746 | LY-2584702 tosylate salt | LY2584702 tosylate | S6 Kinase |
LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer. | |||
T2871 | Quercitrin | Sophoretin,3-rhamnosyl quercetin,Quercetin 3-rhamnoside,Xanthaurine,Meletin | Reactive Oxygen Species , S6 Kinase , Autophagy |
Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities. Quercitrin can be found in a number of food items such as garden tomato (var. ), German cam... | |||
T19913 | CKI-7 | CKI 7 2HCl,CKI-7 dihydrochloride,CKI7 2HCl,CKI 7 dihydrochloride,CKI7 dihydrochloride,CKI-7 2HCl | ROCK , SGK , Casein Kinase , CDK , S6 Kinase |
CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1. |